854646-60-9

Basic information

• Product Name: ethyl 2-methyl-3,5-dinitro-benzoate
• Synonyms: Ethyl 2-methyl-3,5-dinitrobenzoate;Benzoic acid, 2-methyl-3,5-dinitro-, ethyl ester
• CAS NO: 854646-60-9
• Molecular Formula: C₁₀H₁₀N₂O₆
• Molecular Weight: 254.1962
• Mol File: 854646-60-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl 2-methyl-3,5-dinitro-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-methyl-3,5-dinitro-benzoate(854646-60-9)
• EPA Substance Registry System: ethyl 2-methyl-3,5-dinitro-benzoate(854646-60-9)

Safety Data

• Hazardous Substances Data: 854646-60-9(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 39614-85-2 2-methyl-3,5-dinitro-benzoyl chloride 
• 28169-46-2 3,5-dinitro-o-toluic acid 
• 118-90-1 ortho-methylbenzoic acid 
• 141-52-6 sodium ethanolate 

Downstream Products

• 873055-21-1 2-(2-dimethylamino-vinyl)-3,5-dinitro-benzoic acid ethyl ester 
• 952665-27-9 (E)-ethyl 2-(2-(dimethylamino)vinyl)-3,5-dinitrobenzoate 
• 873055-22-2 6-amino-1H-indole-4-carboxylic acid ethyl ester 
• 35572-78-2 2-amino-4,6-dinitrotoluene 
• 148-01-6 zoalene 

Relevant articles and documents

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators of ATP-binding cassette transporters

Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.