85492-86-0

Upstream product

• 62024-36-6 5-chloro-4-oxopentanoic acid methyl ester 
• 930-69-8 sodium thiophenolate 
• 931-59-9 benzenesulfenyl chloride 
• 53856-93-2 methyl 5-bromo-4-oxopentanoate 
• 1490-25-1 succinic acid monomethylester chloride 
• 6089-09-4 4-pentynoic acid 
• 67-56-1 methanol 
• 109574-00-7 (E)-4-(phenylthiomethylene)butan-4-olide 

Downstream Products

• 85493-50-1 5-Benzenesulfinyl-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-((E)-(S)-3-hydroxy-oct-1-enyl)-hexahydro-cyclopenta[b]furan-2-yl]-4-oxo-pentanoic acid methyl ester 
• 85492-98-4 5-[(3aR,4R,5R,6aS)-5-Hydroxy-4-((E)-(S)-3-hydroxy-oct-1-enyl)-hexahydro-cyclopenta[b]furan-2-yl]-4-oxo-5-phenylsulfanyl-pentanoic acid methyl ester 
• 85493-46-5 5-phenyl-sulfinyl-4-oxo-valeric acid-methyl-ester 

Relevant academic research and scientific papers

Thio- and Seleno-lactonizations of Alkynoic Acids

Regio- and stereo-specific thio- and seleno-lactonizations of hept-4-ynoic acid (1a), hex-4-ynoic acid (1b), and pent-4-ynoic acid (1c) can be achieved by treatment of benzenesulphenyl chloride and benzeneselenyl chloride using a hydrogen chloride capture

5-Substituted-4-oxo-PGI1 derivatives, PGI1 compounds of similar structure, their pharmaceutical methods and process for the preparation of said compounds

New PGI1 derivatives are disclosed as well as a process for the preparation thereof, pharmaceutical compositions containing same and methods of treatment employing same. The new compounds are useful to inhibit blood platelet aggregation induced