855-19-6 Usage
Originator
Clostebol acetate,Hunan Steroid
Uses
Clostebol acetate is an anabolic steroid.
This is a controlled substance.
Manufacturing Process
15 g of a mixture of 4β,5-epoxy-etiocholane-17β-ol-3-one and 4β,5-epoxyandrostane-17β-ol-3-one, dissolved in 375 ml chloroform, are treated with a
stream of gaseous HCl at room temperature for about 2 h. The chloroform
solution is neutralized with a sodium bicarbonate solution, washed with water
and dried. The residue is crystallized from benzene or aqueous methanol and
9 g of needle-shaped crystals of 4-chloro-testosterone, melting point 186°-
188°C, are obtained. Upon concentrating the mother-liquor, 3.2 g of thisproduct, melting point 180°-184°C, are covered.
1 g 4-chloro-testosterone are acetylated with 1 ml acetic anhydride and 5 ml
pyridine at room temperature for 16 h. Ice is added to the solution, and the
precipitate is filtered off and recrystallized from chloroform-ethanol; 1 g 4-
chloro-testosterone-acetate, melting point 228°-230°C, is obtained.
Hazard
A poison by ingestion. A reproductive hazard.
Check Digit Verification of cas no
The CAS Registry Mumber 855-19-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,5 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 855-19:
(5*8)+(4*5)+(3*5)+(2*1)+(1*9)=86
86 % 10 = 6
So 855-19-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H29ClO3/c1-12(23)25-18-7-6-14-13-4-5-16-19(22)17(24)9-11-20(16,2)15(13)8-10-21(14,18)3/h13-15,18H,4-11H2,1-3H3/t13-,14-,15-,18-,20+,21-/m0/s1
855-19-6Relevant academic research and scientific papers
A mild preparation of α-halo-α,β-enones from cyclic enones
Righi, Giuliana,Bovicelli, Paolo,Sperandio, Anna
, p. 5889 - 5892 (2007/10/03)
A simple one pot procedure flor the selective transformation of cyclic enones into α-halo-α,β-enones is reported using dimethyldioxirane and metal halides/Amberlyst 15. The method appears particularly appealing for the preparation of labelled molecules for use with the CMIA technique.
Yttrium compounds: New catalysts for the regioselective acylative cleavage of epoxides
Qian,Zhu
, p. 2203 - 2214 (2007/10/02)
The use of Cp2YCl and YCl3 as effective catalysts for the regioselective acylative cleavage of epoxides, especially for the conversion of α,β- epoxyketones to α-chloroenones is described.
The Chlorination of Some Androst-4-en-3-ones by Sulphuryl Chloride
Bourban, Caroline Y. M.,Hanson, James R.,Hitchcock, Peter B.
, p. 2050 - 2066 (2007/10/02)
The chlorination of a number of androst-4-en-3-ones at C4 by sulphuryl chloride is described.The X-ray crystal structure of 4,6-dichloroandrost-4-one-3,11,17-dione has been determined.A simple preparation of 4-chloro-oestrone is reported.
