855282-02-9

Upstream product

• 762-72-1 allyl-trimethyl-silane 
• 19493-09-5 Methylenetriphenylphosphorane 
• 937166-57-9 (2R,3S)-4-(tert-Butyl-diphenyl-silanyloxy)-2,3-bis-methoxymethoxy-butyraldehyde 
• 937166-60-4 (2S,3S)-4-(tert-butyl(diphenyl)silyloxy)-2,3-bis(methoxymethoxy)butan-1-ol 
• 855282-22-3 (4S,5S,6R)-5,6-dihydroxy-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-methoxy-1-heptene 
• 855282-24-5 (2R,3S,4S)-1-(tert-Butyl-diphenyl-silanyloxy)-4-methoxy-3-methoxymethoxy-5,5-dimethyl-hept-6-en-2-ol 
• 855282-04-1 (4S,5R,6R)-5,6-bis(methoxymethoxy)-3,3-dimethyl-7-[(1,1-dimethylethyl)diphenylsilyl]oxy-4-hydroxy-1-heptene 
• 855282-51-8 tert-Butyl-((2R,3R,4S)-4-methoxy-2,3-bis-methoxymethoxy-5,5-dimethyl-hept-6-enyloxy)-diphenyl-silane 
• 855282-55-2 Benzoic acid (1R,2R,3S)-1-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-3-methoxy-4,4-dimethyl-hex-5-enyl ester 
• 855282-57-4 Benzoic acid (1R,2R,3S)-1-(tert-butyl-diphenyl-silanyloxymethyl)-3-methoxy-2-methoxymethoxy-4,4-dimethyl-hex-5-enyl ester 

Relevant academic research and scientific papers

Direct carbinolamide synthesis

Carbinolamides were prepared by treatment of aldehydes with carboxamides in the presence of dicyclohexylboron chloride and triethylamine. All carbinolamide products were stable to isolation, purification and routine handling.

Total synthesis of mycalamide A

This communication describes a concise and efficient total synthesis of mycalamide A by the convergent coupling of pederic acid unit with the mycalamine unit. The left-half, (+)-7-benzoylpederic acid, was synthesized from (2R,3R)-3-methylpent-4-en-2-ol in