85539-73-7

Upstream product

• 101226-10-2 tert-butyl 5-oxo-5-(1,3-dithian-2-yl)pentanoate 
• 52783-56-9 sodium monomethyl glutaric carboxylate 
• 58277-27-3 2-(4-methoxycarbonylbutyryl)-1,3-dithiane 
• 101226-16-8 tert-butyl 5(S)-(benzoyloxy)-5-(1,3-dithian-2-yl)pentanoate 
• 1501-27-5 Pentanedioic acid, monomethyl ester 
• 85539-72-6 (S)-5-[1,3]Dithian-2-yl-5-hydroxy-pentanoic acid methyl ester 
• 98-88-4 benzoyl chloride 
• 186581-53-3 diazomethane 
• 101226-11-3 tert-butyl 5(S)-hydroxy-5-(1,3-dithian-2-yl)pentanoate 
• 85539-71-5 5-oxo-5-(1,3-dithian-2-yl)pentanoic acid 

Downstream Products

• 76745-20-5 Methyl 5S-benzoyloxy-5-formylvalerate 
• 71160-24-2 Leukotriene B 
• 76745-31-8 methyl 5(S)-(benzoyloxy)-12(R)-hydroxy-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 
• 101226-20-4 methyl 5(S)-(benzoyloxy)-12(R)-(tert-butyldiphenylsiloxy)-6(Z),8(E),10(E),14(Z)-eicosatetraenoate 
• 101226-21-5 Benzoic acid (2Z,4E,6E,10E)-(1S,8R)-8-(tert-butyl-diphenyl-silanyloxy)-1-(3-methoxycarbonyl-propyl)-hexadeca-2,4,6,10-tetraenyl ester 

Relevant academic research and scientific papers

A Chemoenzymatic Synthesis of Leukotriene B4

A total synthesis of leukotriene B4 (1) is accomplished by the assembly of the key chirons 2 and 3, which are prepared via enzymatic methods.

BIFUNCTIONAL CHIRAL SYNTHONS VIA MICROBIOLOGICAL METHODS. 2. OPTICALLY-ACTIVE α-HYDROXY ALDEHYDES.

A versatile chemical-microbiological approach has been developed for the preparation of chiral α-hydroxy aldehydes via stereoselective reduction of the corresponding α-keto thioacetals or via optical resolution of the racemic α-acetoxy esters.