855475-24-0

Upstream product

• 1279696-96-6 (2R,4S)-3-[(4-methylphenyl)sulfonyl]-4-(phenylmethyl)-1,2,3-oxathiazolidine 2-oxide 
• 100-52-7 benzaldehyde 
• 4039-32-1 lithium hexamethyldisilazane 
• 2633-66-1 2-mesitylmagnesium bromide 
• 607729-50-0 (S)-(+)-2,4,6-trimethylbenzenesulfinamide 

Downstream Products

• 607729-55-5 diethyl (S_S,2S,3R)-(+)-N-(mesitylsulfinyl)-3-phenylaziridine-2-phosphonate 
• 6668-27-5 (S)-2-methyl-1-phenylpropane-1-amine 
• 1315318-10-5 (S)-2,4,6-trimethyl-N-((S)-2-methyl-1-phenylpropyl)-benzenesulfinamide 
• 220586-54-9 diethyl(-)-(2S,3R)-(3-phenyl-2-H-aziridin-2-yl) phosphonate 

Relevant academic research and scientific papers

Asymmetric radical alkylation of: N -sulfinimines under visible light photocatalytic conditions

In this communication, a new photocatalytic strategy for the addition of alkyl-radical derivatives to N-sulfinimines with complete diastereoselectivity and moderate to good yields is presented. This is the first asymmetric photocatalytic addition to N-sulfinimines under visible light irradiation with smooth conditions and functional group tolerance.

Multicomponent synthesis of chiral sulfinimines

Two oxathiozolidine-S-oxide templates have been developed and used in a four-component coupling protocol for the synthesis of a wide range of chiral sulfinimines in high enantiomeric excesses. The templates can be synthesized from cheap commodity chemicals in three steps in high yields. Furthermore the template is easily recovered in high yields for recycling.

Asymmetric synthesis of syn-α-substituted β-amino ketones by using sulfinimines and prochiral weinreb amide enolates

syn-α-Substituted β-amino Weinreb amides are new chiral building blocks for asymmetric synthesis of syn-α-substituted β-amino acids, aldehydes, and ketones and are prepared by addition of prochiral lithium enolates of Weinreb amides to sulfinimines (N-sul

Improved asymmetric synthesis of aziridine 2-phosphonates using (S)-(+)-2,4,6-trimethylphenylsulfinamide

The aza-Darzens reaction of lithium diethyl iodomethylphosphonate with enantiopure N-(2,4,6-trimethylphenylsulfinyl)imines affords a single diastereomeric N-sulfinylaziridine 2-phosphonate which, on treatment with MeMgBr, gives the corresponding NH-azirid