85571-48-8

Upstream product

• 39687-95-1 isocyanoacetic acid methyl ester 
• 98-86-2 acetophenone 

Downstream Products

• 85564-51-8 methyl 2-isocyano-3-phenyl-2-butenoate 
• 85564-25-6 2-Ethyl-2-isocyano-3-phenyl-but-3-enoic acid methyl ester 
• 85571-52-4 (Z)-methyl 2-isocyano-3-phenylbut-2-enoate 
• 85564-51-8 (E)-methyl 2-isocyano-3-phenylbut-2-enoate 
• 1610565-28-0 methyl 4-methyl-1-phenylisoquinoline-3-carboxylate 
• 194224-11-8 4-methyl-1-phenylisoquinoline-3-carboxylic acid 
• 1610565-64-4 C₁₈H₁₄BrNO₂ 

Relevant academic research and scientific papers

Metal-Free Radical Cyclization of Vinyl Isocyanides with Alkanes: Synthesis of 1-Alkylisoquinolines

A metal-free radical cyclization reaction of vinyl isocyanides with alkanes is developed, allowing convenient access to a diverse range of potentially valuable 1-alkylisoquinolines. The methodology is simple and efficient, demonstrating excellent functional group tolerance and broad substrate scope. A mechanism involving a radical process is supported by kinetic isotope effect and radical inhibition studies.

Synthesis of isoquinolines via visible light-promoted insertion of vinyl isocyanides with diaryliodonium salts

A synthetic strategy for multi-substituted isoquinoline derivatives has been developed using visible light-promoted vinyl isocyanide insertion with diaryliodonium salts at room temperature. The methodology presented here represents the first example of is