85571-52-4

Upstream product

• 85571-48-8 (E)-2-Formylamino-3-phenyl-but-2-enoic acid methyl ester 
• 98-86-2 acetophenone 

Downstream Products

• 85564-25-6 2-Ethyl-2-isocyano-3-phenyl-but-3-enoic acid methyl ester 
• 194224-11-8 4-methyl-1-phenylisoquinoline-3-carboxylic acid 
• 1610565-64-4 C₁₈H₁₄BrNO₂ 
• 1610565-28-0 methyl 4-methyl-1-phenylisoquinoline-3-carboxylate 

Relevant academic research and scientific papers

Metal-Free Radical Cyclization of Vinyl Isocyanides with Alkanes: Synthesis of 1-Alkylisoquinolines

A metal-free radical cyclization reaction of vinyl isocyanides with alkanes is developed, allowing convenient access to a diverse range of potentially valuable 1-alkylisoquinolines. The methodology is simple and efficient, demonstrating excellent functional group tolerance and broad substrate scope. A mechanism involving a radical process is supported by kinetic isotope effect and radical inhibition studies.

Synthesis of isoquinolines via visible light-promoted insertion of vinyl isocyanides with diaryliodonium salts

A synthetic strategy for multi-substituted isoquinoline derivatives has been developed using visible light-promoted vinyl isocyanide insertion with diaryliodonium salts at room temperature. The methodology presented here represents the first example of is

Syntheses of α-Alkylated β,γ-Unsaturated α-Amino Acids

Various α-alkylated β,γ-unsaturated α-amino acids were synthesized by the deconjugative alkylation of methyl α-isocyanoalkylidenesacetates followed by hydrolysis.In the mechanistic study, no marked differences in reactivity of geometrical isomers of methy