85613-45-2

Usage

Aromatic heterocycle

1H-Imidazole, 2-[4-(oxiranylmethoxy)phenyl]is a derivative of imidazole, which is a five-membered aromatic ring with two non-adjacent nitrogen atoms.

Substitution on phenyl group

The compound features a substituted phenyl group with an oxirane ring attached to it.

Epoxy ring

The oxiranylmethoxy group in the compound is a functional group that contains an epoxy ring, also known as a three-membered cyclic ether, which adds reactivity to the molecule.

Applications in organic synthesis

1H-Imidazole, 2-[4-(oxiranylmethoxy)phenyl]may be used as a building block for the synthesis of various drug candidates.

Use in pharmaceuticals

The compound may have potential uses in the pharmaceutical industry.

Material science applications

The compound may be used as a starting material for the preparation of polymers and other chemical products.

Upstream product

• 85613-29-2 Methanesulfonic acid 2-hydroxy-3-[4-(1H-imidazol-2-yl)-phenoxy]-propyl ester 
• 123-08-0 4-hydroxy-benzaldehyde 
• 584-08-7 potassium carbonate 
• 124-63-0 methanesulfonyl chloride 
• 85613-28-1 3-[p-(2-imidazolyl)phenoxy]-1,2-propanediol 
• 85613-27-0 3--1,2-propanediol acetonide 
• 91944-48-8 4-[(4-formylphenoxy)methyl]-2,2-dimethyl-1,3-dioxolane 

Downstream Products

• 126007-86-1 1-phenyl-3-<2-<<2-hydroxy-3-<4-(2-imidazolyl)phenoxy>propyl>amino>ethyl>urea 
• 91944-34-2 2-[[p-[3-[2-(3,4-Dimethoxyphenyl)ethylamino]-2-hydroxypropoxy]phenyl]]imidazole 
• 85613-31-6 2-[p-(3-Cyclopropylamino-2-hydroxypropoxy)phenyl]-imidazole 

Relevant academic research and scientific papers

BETA-BLOCKING SUBSTITUTED IMIDAZOLES

Novel substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and β-adrenergic blocking activity.

BETA-ADRENERGIC BLOCKING IMIDAZOLYLPHENOXY PROPANOLAMINES

Substituted imidazoles and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and β-adrenergic blocking activity. STR1

3-AMINO-2-HYDROXYPROPOXYARYL IMIDAZOLE DERIVATIVES

Novel substituted imidazoles of the formula STR1 and methods for their preparation are disclosed. These imidazoles, and their salts, exhibit pharmacological activity which includes antihypertensive activity and β-adrenergic blocking activity.

β1-Selective adrenoceptor antagonists: Examples of the 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazole class

A series of 2-[4-[3-(substituted-amino)-2-hydroxypropoxy]phenyl]imidazoles is described. The compounds were investigated in vitro for β-adrenoceptor antagonism, and several examples were found to be selective for the β1-adrenoceptor. The structure-activity relationship exhibited by this series of compounds is discussed. (S)-2-[p-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-2-hydroxypropoxy]phenyl] -4-(2-thienyl)imidazole [(S)-13] was over 100 times more selective than atenolol for the β1-adrenergic receptor and has been selected for in-depth studies.