856414-68-1

Basic information

• Product Name: 3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER
• Synonyms: ETHYL 3-OXO-3-(TETRAHYDRO-2H-PYRAN-4-YL)PROPANOATE;3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER;TETRAHYDRO-BETA-OXO-2H-PYRAN-4-PROPANOIC ACID ETHYL ESTER;Ethyl 3-Oxo-3-(4-tetrahydropyranyl)propanoate;3-Oxo-3-(tetrahydro-2H-pyran-4-yl)propanoic acid ethyl ester;Ethyl 3-oxo-3-(tetrahydropyran-4-yl)propanoate;Ethyl 3-oxo-3-(tetrahydropyran-4-yl)propionate;Ethyl 3-oxo-3-(tetrahydro-2H-pyran-4-yl)
• CAS NO: 856414-68-1
• Molecular Formula: C10H16O4
• Molecular Weight: 200.23
• Product Categories: pharmacetical
• Mol File: 856414-68-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 287.7±30.0 °C(Predicted)
• Appearance: /
• Density: 1.101±0.06 g/cm3(Predicted)
• PKA: 10.32±0.20(Predicted)
• CAS DataBase Reference: 3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER(856414-68-1)
• EPA Substance Registry System: 3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER(856414-68-1)

Safety Data

• Hazardous Substances Data: 856414-68-1(Hazardous Substances Data)

Usage

General Description

3-OXO-3-(Tetrahydro-pyran-4-yl)-propionic acid ethyl ester is a chemical compound that belongs to the class of organic compounds known as pyranols. It is a colorless liquid with a molecular formula of C10H16O3. 3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical drugs. Its main applications include the production of anti-inflammatory and analgesic drugs. Additionally, it is also used in the synthesis of fragrances and flavor compounds. 3-OXO-3-(TETRAHYDRO-PYRAN-4-YL)-PROPIONIC ACID ETHYL ESTER has potential biological activity and is being studied for its potential medicinal and therapeutic properties.

Upstream product

• 110238-91-0 tetrahydropyran-4-carboxylic acid methyl ester 
• 141-78-6 ethyl acetate 
• 5337-03-1 tetrahydro-2H-pyran-4-carboxylic acid 
• 6148-64-7 ethyl potassium malonate 
• 137052-08-5 1-(tetrahydro-2H-pyran-4-yl)ethan-1-one 
• 105-58-8 Diethyl carbonate 

Relevant articles and documents

METHOD OF MAKING AZAINDAZOLE DERIVATIVES

Disclosed are methods, reagents, and intermediates useful for making azaindazole derivatives, which may be used to modulate Glucokinase. The disclosed methods and materials are generally useful for making halo-esters and sulfonyl-substituted compounds.

PROCESSES FOR PRODUCING ALKYL 3-(4-TETRAHYDROPYRANYL)-3-OXOPROPIONATE COMPOUND AND 4-ACYLTETRAHYDROPYRAN

The present invention is to provide a process for preparing an alkyl 3-(4-tetrahydropyranyl)-3-oxopropanoate compound represented by the formula (1): wherein R1 and R2 may be the same or different from each other, and represent a group which does not participate in the reaction, and R1 and R2 may be bonded to form a ring, and the ring may contain a hetero atom(s), and R3 represents a hydrocarbon group, which comprises reacting 4-acyltetrahydropyran represented by the formula (2): wherein R1 and R2 have the same meanings as defined above, and a carbonic acid diester represented by the formula (3): wherein R3 has the same meanings as defined above, and two R3s may be bonded to each other to form a ring, in the presence of a base, and a process for preparing 4-acyltetrahydropyran.