85666-05-3Relevant academic research and scientific papers
Tandem heck/decarboxylation/heck strategy: Protecting-group-free synthesis of symmetric and unsymmetric hydroxylated stilbenoids
Shard, Amit,Sharma, Naina,Bharti, Richa,Dadhwal, Sumit,Kumar, Rajesh,Sinha, Arun K.
supporting information, p. 12250 - 12253 (2013/02/22)
Ride the (micro)wave: The title strategy has been developed for the synthesis of various symmetric or unsymmetric hydroxylated stilbenoids utilizing 4-halophenols and acrylic acid as coupling partners (see scheme; DMA=N,N-dimethylacetamide, MW=microwave). Protecting groups are not necessary and a single palladium catalyst is used. Copyright
Synthesis and anti-inflammatory activity of resveratrol analogs
Chen, Guoliang,Shan, Wei,Wu, Yingliang,Ren, Lixiang,Dong, Jinhua,Ji, Zhizhong
, p. 1587 - 1590 (2007/10/03)
Seventeen novel resveratrol derivatives were synthesized. Their anti-inflammatory activities were tested on xylene-induced mouse ear edema. The pharmacological results showed that some compounds have potent anti-inflammatory activities.
Antiinflammatory 2,6-Di-tert-butyl-4-(2-arylethenyl)phenols
Lazer, Edward S.,Wong, Hin-Chor,Possanza, Genus J.,Graham, Anne G.,Farina, Peter R.
, p. 100 - 104 (2007/10/02)
A series of 2,6-di-tert-butyl-4-(2-arylethenyl)phenols was prepared and examined for their ability to inhibit cyclooxygenase and 5-lipoxygenase in vitro and developing adjuvant arthritis in vivo in the rat.Structure-activity relationships are discussed.Am
Pyridyl-substituted-benzofurans
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, (2008/06/13)
The present invention provides novel pyridinyl-benzofurans and derivatives thereof which are useful as thromboxane A2 (TXA2) synthetase inhibitors and as such represent potent pharmacological agents.
