857086-94-3 Usage
Uses
Used in Pharmaceutical Industry:
(1R,2R)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol is used as an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), a diarylquinoline derivative that acts as a mycobacterial inhibitor. This makes it a crucial component in the development of new drugs for the treatment of tuberculosis and other mycobacterial infections.
As an intermediate in the synthesis of other pharmaceuticals:
Due to its unique structure and functional groups, (1R,2R)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(methylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol can be used as a starting material or intermediate in the synthesis of other pharmaceutical compounds with potential therapeutic applications. Its versatility in chemical reactions allows for the development of new drugs with improved efficacy and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 857086-94-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,0,8 and 6 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 857086-94:
(8*8)+(7*5)+(6*7)+(5*0)+(4*8)+(3*6)+(2*9)+(1*4)=213
213 % 10 = 3
So 857086-94-3 is a valid CAS Registry Number.
857086-94-3Relevant academic research and scientific papers
Practical syntheses of (2S)-R207910 and (2R)-R207910
Chandrasekhar, Srivari,Babu, G. S. Kiran,Mohapatra, Debendra K.
, p. 2057 - 2061 (2011/05/09)
Concise and practical syntheses of (2S)-R207910 (3a) and (2R)-R207910 (3b) have been achieved in high overall yield of 12 % in 10 steps for each isomer starting from a known intermediate following Sharpless asymmetric epoxidation, regioselective epoxide opening, modified allylzinc bromide addition as key reactions. Copyright
