857250-43-2

Basic information

• Product Name: {[[2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-methyl}-phosphonic acid diphenyl ester
• CAS NO: 857250-43-2
• Molecular Weight: 833.88
• Mol File: 857250-43-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {[[2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-methyl}-phosphonic acid diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {[[2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-methyl}-phosphonic acid diphenyl ester(857250-43-2)
• EPA Substance Registry System: {[[2-(4-Benzoylamino-2-oxo-2H-pyrimidin-1-yl)-acetyl]-(2-{[(4-methoxy-phenyl)-diphenyl-methyl]-amino}-ethyl)-amino]-methyl}-phosphonic acid diphenyl ester(857250-43-2)

Safety Data

• Hazardous Substances Data: 857250-43-2(Hazardous Substances Data)

Upstream product

• 168263-86-3 N⁴-benzoylcytosine-1-acetic acid 
• 203643-15-6 N-<2-(4-monomethoxytrityl)aminoethyl>aminomethyldiphenyl phosphonate 
• 4712-55-4 diphenyl hydrogen phosphite 
• 114729-69-0 N¹-((4-methoxyphenyl)diphenylmethyl)ethane-1,2-diamine 

Relevant articles and documents

Synthesis and binding study of phosphonate analogues of PNAs and their hybrids with PNAs

The preparation of monomers for the synthesis of phosphonate analogues of peptide nucleic acids containing the four natural nucleobases: thymine, cytosine, adenine and guanine, has been accomplished. The monomers obtained were used for the automated online solid phase synthesis of pure phosphono- PNA oligomers as well as chimeras consisting of phosphono-PNA and PNA resudies. The hybridization properties of these oligonucleotide mimics to complementary DNA and RNA fragments were studied.