857447-92-8 Usage
Description
ABT-751 is a microtubule inhibitor that possesses antitumor activity through the induction of reactive oxygen species.
Uses
Used in Pharmaceutical Industry:
ABT-751 is used as an antitumor agent for inducing antitumor activity against multidrug-resistant recurrent neuroblastoma xenograft mouse models. It is particularly effective when used synergistically with fenretinide, enhancing its therapeutic potential in combating cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 857447-92-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,4,4 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 857447-92:
(8*8)+(7*5)+(6*7)+(5*4)+(4*4)+(3*7)+(2*9)+(1*2)=218
218 % 10 = 8
So 857447-92-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20)
857447-92-8Relevant articles and documents
N-(2-((4-HYDROXYPHENYL)AMINO)PYRIDIN-3-YL)-4-METHOXYBENZENESULFONAMIDE CRYSTALLINE FORM 1
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Page/Page column 16, (2008/06/13)
N-(2-((4-Hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide Crystalline Form 1, ways to make it, compositions containing it and methods of treatment of diseases using it are disclosed.
Amorphous N-(2-((4-hydroxyphenyl)amino)pyridin-3-yl)-4-methoxybenzenesulfonamide
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Page/Page column 2, (2008/06/13)
An amorphous drug, processes for making it, compositions containing it and methods of treatment of diseases using it are disclosed.
Novel Sulfonamides as Potential, Systemically Active Antitumor Agents
Yoshino, Hiroshi,Ueda, Norihiro,Niijima, Jun,Sugumi, Hiroyuki,Kotake, Yoshihiko,et al.
, p. 2496 - 2497 (2007/10/02)
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