857568-96-8Relevant academic research and scientific papers
Design, synthesis and antimalarial activity of some new 2-hydroxy-1,4-naphthoquinone-4-hydroxyaniline hybrid mannich bases
Sharma, Dipshikha,Chetia, Dipak,Rudrapal, Mithun
, p. 782 - 788 (2016)
In this study, some novel 2-hydroxy-1,4-naphthoquinone-4-hydroxyaniline hybrid Mannich bases were designed, synthesized and evaluated for in vitro antimalarial activity. The design strategy of novel hybrid molecules involves fusion between the pharmacopho
Synthesis and in vitro and in vivo antimalarial activity of novel 4-anilinoquinoline Mannich base derivatives
Singh, Bhupendra,Chetia, Dipak,Puri,Srivastava, Kumkum,Prakash, Anil
experimental part, p. 1523 - 1529 (2012/06/05)
Development of resistance has severely limited the choice of available antimalarial drugs, which clearly highlights the urgent need of novel chemotherapeutic agents for the treatment of malaria. The purpose of this study was to develop new potential antim
