Welcome to LookChem.com Sign In|Join Free
  • or
4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone is a chemical compound with the molecular formula C16H15N3O2. It is a derivative of cyclohexanone with substituents including a hydroxyl group and a pyridine ring. 4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone is a key intermediate in the synthesis of pharmaceuticals and agrochemicals, and it also has potential applications in the field of materials science. Its structural features make it valuable for studies in organic chemistry and for the development of new synthetic routes. Additionally, the presence of a pyrimidine moiety in its structure suggests potential biological activity, making it a subject of interest for drug discovery and development.

857651-06-0

Post Buying Request

857651-06-0 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

857651-06-0 Usage

Uses

Used in Pharmaceutical Industry:
4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone is used as a key intermediate in the synthesis of pharmaceuticals for its potential biological activity and structural features that enable the development of new synthetic routes.
Used in Agrochemical Industry:
4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone is used as a key intermediate in the synthesis of agrochemicals for its potential applications in the development of new synthetic routes and its structural features.
Used in Materials Science:
4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone is used in the field of materials science for its potential applications in the development of new materials and its structural features that enable studies in organic chemistry.
Used in Drug Discovery and Development:
4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone is used in drug discovery and development due to the presence of a pyrimidine moiety in its structure, which suggests potential biological activity.

Check Digit Verification of cas no

The CAS Registry Mumber 857651-06-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,7,6,5 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 857651-06:
(8*8)+(7*5)+(6*7)+(5*6)+(4*5)+(3*1)+(2*0)+(1*6)=200
200 % 10 = 0
So 857651-06-0 is a valid CAS Registry Number.

857651-06-0Downstream Products

857651-06-0Relevant academic research and scientific papers

Discovery of INCB8761/PF-4136309, a potent, selective, and orally bioavailable CCR2 antagonist

Xue, Chu-Biao,Wang, Anlai,Han, Qi,Zhang, Yingxin,Cao, Ganfeng,Feng, Hao,Huang, Taisheng,Zheng, Changsheng,Xia, Michael,Zhang, Ke,Kong, Lingquan,Glenn, Joseph,Anand, Rajan,Meloni, David,Robinson,Shao, Lixin,Storace, Lou,Li, Mei,Hughes, Robert O.,Devraj, Rajesh,Morton, Philip A.,Rogier, D. Joseph,Covington, Maryanne,Scherle, Peggy,Diamond, Sharon,Emm, Tom,Yeleswaram, Swamy,Contel, Nancy,Vaddi, Kris,Newton, Robert,Hollis, Greg,Metcalf, Brian

supporting information; experimental part, p. 913 - 918 (2012/02/13)

We report the discovery of a new (S)-3-aminopyrrolidine series of CCR2 antagonists. Structure-activity relationship studies on this new series led to the identification of 17 (INCB8761/PF-4136309) that exhibited potent CCR2 antagonistic activity, high sel

3-Cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors

-

Page/Page column 35, (2008/06/13)

The present invention relates to 3-cycloalkylaminopyrrolidine derivatives of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, X, Y and Z are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as modulators of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 857651-06-0