857685-62-2

Upstream product

• 100100-47-8 (+)-2-oxabicyclo<3.3.0>octan-3-one 
• 4934-95-6 methyl 2-(2-oxocyclopentyl)acetate 
• 857685-60-0 (2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone 
• 857685-58-6 (3R,3aR,6aR)-3-methyl-hexahydrocyclopenta[b]furan-2-one 

Downstream Products

• 857685-65-5 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-(3''-iodo-propyl)-2-(S)-nitro-cyclopentane 
• 857685-64-4 (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-(3-hydroxypropyl)-2-nitro-cyclopentane 
• 857685-74-6 [(1R,5S,7R)-1-((R)-2-Benzyloxy-1-methyl-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-acetaldehyde 
• 857685-70-2 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-7-(R)-[2''-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-aza-5-(S)-spiro[4.5]decane 
• 857685-72-4 (1R,5S,7R)-7-(2-hydroxyethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane 
• 857685-67-7 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-nitro-2-[6''-(tert-butyl-dimethyl-silanyloxy)-4''-oxo-hexyl]-cyclopentane 
• 857685-71-3 (1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane 
• 857685-66-6 (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitro-2-[3-(2-{2-[(tert-butyl)dimethylsilanyloxy]ethyl}-1,3-dithian-2-yl)propyl]-cyclopentane 
• 857685-75-7 (1'R,5'S,7'R,1''R)-4-{1'-[2''-benzyloxy-1''-methyl-ethyl]-6'-trifluoroacetyl-6'-aza-5'-spiro[4.5]dec-7'-yl}-2-methylbut-2E-enoic acid ethyl ester 
• 945223-16-5 C₂₇H₄₅NO₂Si 
• 857685-69-9 (1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-hydroxy-6-azaspiro[4.5]decane 
• 857685-68-8 (1R,5S)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-azaspiro[4.5]dec-6-en-6-oxide 
• 857685-63-3 3-[1'-(S)-nitro-2'-(R)-(2''-benzyloxy-1''-(R)-methylethyl)-cyclopentyl]-propionic acid methyl ester 

Relevant academic research and scientific papers

An enantioselective total synthesis of pinnaic acid

An enantioselective and convergent total synthesis of marine natural product pinnaic acid has been achieved. Our general synthetic approach is featured with an asymmetric hydrogenation of racemic γ-keto ester 3, a diastereoselective methylation on the α-m