857685-69-9

Upstream product

• 857685-61-1 (2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone oxime 
• 857685-62-2 (1R)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitrocyclopentane 
• 857685-66-6 (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitro-2-[3-(2-{2-[(tert-butyl)dimethylsilanyloxy]ethyl}-1,3-dithian-2-yl)propyl]-cyclopentane 
• 857685-67-7 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-nitro-2-[6''-(tert-butyl-dimethyl-silanyloxy)-4''-oxo-hexyl]-cyclopentane 
• 857685-64-4 (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-(3-hydroxypropyl)-2-nitro-cyclopentane 
• 857685-63-3 3-[1'-(S)-nitro-2'-(R)-(2''-benzyloxy-1''-(R)-methylethyl)-cyclopentyl]-propionic acid methyl ester 
• 857685-65-5 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-(3''-iodo-propyl)-2-(S)-nitro-cyclopentane 
• 857685-68-8 (1R,5S)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-azaspiro[4.5]dec-6-en-6-oxide 

Downstream Products

• 857685-74-6 [(1R,5S,7R)-1-((R)-2-Benzyloxy-1-methyl-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-acetaldehyde 
• 857685-72-4 (1R,5S,7R)-7-(2-hydroxyethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane 
• 857685-71-3 (1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane 
• 857685-75-7 (1'R,5'S,7'R,1''R)-4-{1'-[2''-benzyloxy-1''-methyl-ethyl]-6'-trifluoroacetyl-6'-aza-5'-spiro[4.5]dec-7'-yl}-2-methylbut-2E-enoic acid ethyl ester 
• 857685-70-2 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-7-(R)-[2''-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-aza-5-(S)-spiro[4.5]decane 

Relevant academic research and scientific papers

An efficient and enantioselective approach to the azaspirocyclic core of alkaloids: Formal synthesis of halichlorine and pinnaic acid

A novel, highly stereoselective synthesis of an azaspirocyclic core, which contains four stereogenic carbons consistent with structures of natural halichlorine and pinnaic acid, is presented. Lipase PS-catalyzed selective acylation, asymmetric methylation