857685-63-3

Upstream product

• 100100-47-8 (+)-2-oxabicyclo<3.3.0>octan-3-one 
• 4934-95-6 methyl 2-(2-oxocyclopentyl)acetate 
• 857685-61-1 (2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone oxime 
• 857685-60-0 (2R)-2-((1R)-2-benzyloxy-1-methylethyl)-cyclopentanone 
• 857685-58-6 (3R,3aR,6aR)-3-methyl-hexahydrocyclopenta[b]furan-2-one 
• 857685-62-2 (1R)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitrocyclopentane 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 857685-69-9 (1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-hydroxy-6-azaspiro[4.5]decane 
• 857685-68-8 (1R,5S)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-azaspiro[4.5]dec-6-en-6-oxide 
• 945223-16-5 C₂₇H₄₅NO₂Si 
• 857685-75-7 (1'R,5'S,7'R,1''R)-4-{1'-[2''-benzyloxy-1''-methyl-ethyl]-6'-trifluoroacetyl-6'-aza-5'-spiro[4.5]dec-7'-yl}-2-methylbut-2E-enoic acid ethyl ester 
• 857685-66-6 (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-nitro-2-[3-(2-{2-[(tert-butyl)dimethylsilanyloxy]ethyl}-1,3-dithian-2-yl)propyl]-cyclopentane 
• 857685-71-3 (1R,5S,7R)-7-(2-((tert-butyl)dimethylsilanyloxy)ethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane 
• 857685-67-7 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-nitro-2-[6''-(tert-butyl-dimethyl-silanyloxy)-4''-oxo-hexyl]-cyclopentane 
• 857685-72-4 (1R,5S,7R)-7-(2-hydroxyethyl)-1-((1R)-2-benzyloxy-1-methylethyl)-6-trifluoroacetyl-6-azaspiro[4.5]decane 
• 857685-70-2 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-7-(R)-[2''-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-aza-5-(S)-spiro[4.5]decane 
• 857685-74-6 [(1R,5S,7R)-1-((R)-2-Benzyloxy-1-methyl-ethyl)-6-(2,2,2-trifluoro-acetyl)-6-aza-spiro[4.5]dec-7-yl]-acetaldehyde 
• 857685-65-5 1-(R)-(2'-benzyloxy-1'-(R)-methyl-ethyl)-2-(S)-(3''-iodo-propyl)-2-(S)-nitro-cyclopentane 
• 857685-64-4 (1R,2S)-1-((1R)-2-benzyloxy-1-methylethyl)-2-(3-hydroxypropyl)-2-nitro-cyclopentane 

Relevant academic research and scientific papers

An enantioselective total synthesis of pinnaic acid

An enantioselective and convergent total synthesis of marine natural product pinnaic acid has been achieved. Our general synthetic approach is featured with an asymmetric hydrogenation of racemic γ-keto ester 3, a diastereoselective methylation on the α-m

An efficient and enantioselective approach to the azaspirocyclic core of alkaloids: Formal synthesis of halichlorine and pinnaic acid

A novel, highly stereoselective synthesis of an azaspirocyclic core, which contains four stereogenic carbons consistent with structures of natural halichlorine and pinnaic acid, is presented. Lipase PS-catalyzed selective acylation, asymmetric methylation