85809-21-8Relevant academic research and scientific papers
NUCLEOPHILIC CLEAVAGE OF 2,2-DIMETHYLAZIRIDINES: COMPETITION BETWEEN SN2 AND POSTULATED "SET" MECHANISM.
Stamm, H.,Assithianakis, P.,Buchholz, B.,Weiss, R.
, p. 5021 - 5024 (2007/10/02)
Regioselectivity of nucleophilic attack on 2,2-dimethylaziridines depends on the degree of leaving group activation: in highly activated aziridines it occures at the methylene carbon and in less activated at the tertiary carbon.This latter abnormal ring opening is explained by an SET mechanism.
