85809-60-5Relevant academic research and scientific papers
STEREOSELECTIVE SYNTHESIS OF 2-ALKYLIDENE-3,4-DIHYDRO-3-OXO-2H-1,4-BENZOTHIAZINES
Babudri, F.,Nunno, L. Di,Florio, S.
, p. 3059 - 3065 (2007/10/02)
Metallation of 4-methyl-3,4-dihydro-3-oxo-2H-1,4-benzothiazine with LDA and subsequent reaction with aldehydes leads to diastereomeric aldols 4 and 5.Acetylation followed by acetic acid elimination of the aldols provides a stereoselective and high yield route to 2-alkylidene-3,4-dihydro-3-oxo-2H-1,4-benzothiazines.
