858099-76-0Relevant academic research and scientific papers
Controlling the morphology of cross β-sheet assemblies by rational design
Deechongkit, Songpon,Powers, Evan T.,You, Shu-Li,Kelly, Jeffery W.
, p. 8562 - 8570 (2007/10/03)
Low molecular weight peptidomimetics with simple amphiphilic sequences can help to elucidate the structures of cross β-sheet assemblies, such as amyloid fibrils. The peptidomimetics described herein comprise a dibenzofuran template, two peptide strands ma
Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly: Implications for amyloid fibril formation and materials science
Lashuel, Hilal A.,LaBrenz, Steven R.,Woo, Linda,Serpell, Louise C.,Kelly, Jeffery W.
, p. 5262 - 5277 (2007/10/03)
Deciphering the mechanism(s) of β-sheet mediated self-assembly is essential for understanding amyloid fibril formation and for the fabrication of polypeptide materials. Herein, we report a simple peptidomimetic that self-assembles into polymorphic β-sheet
