858136-18-2Relevant academic research and scientific papers
9-anilinoacridine alkylating agents
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, (2008/12/07)
This invention relates to 9-anilinoacridine alkylating agents, their synthesis and their use in pharmaceutical compositions for treating diseases.
Potent antitumor 9-anilinoacridines bearing an alkylating N-mustard residue on the anilino ring: Synthesis and biological activity
Bacherikov, Valeriy A.,Chou, Ting-Chao,Dong, Hua-Jin,Zhang, Xiuguo,Chen, Ching-Huang,Lin, Yi-Wen,Tsai, Tsong-Jen,Lee, Rong-Zau,Liu, Leroy F.,Su, Tsann-Long
, p. 3993 - 4006 (2007/10/03)
A series of N-mustard derivatives of 9-anilinoacridine was synthesized for antitumor and structure-activity relationship studies. The alkylating N-mustard residue was linked to the C-3′ or C-4′ position of the anilino ring with an O-ethylene (O-C2/s
