858245-54-2Relevant academic research and scientific papers
Bifunctional phosphine ligand-enabled gold-catalyzed direct cycloisomerization of alkynyl ketones to 2,5-disubstituted furans
Hu, Xiaojun,Zhou, Bingwei,Jin, Hongwei,Liu, Yunkui,Zhang, Liming
, p. 7297 - 7300 (2020/07/14)
An efficient synthesis of 2,5-disubstituted furans directly from alkynyl ketones has been developed via tandem gold(i)-catalyzed isomerization of alkynyl ketones to allenyl ketones and cycloisomerization. The key to the success of this chemistry is the use of a biphenyl-2-ylphosphine ligand featuring a critical remote tertiary amino group.
Preparation method of 2,5-disubstituted furan derivatives
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Paragraph 0039-0042, (2019/08/30)
The invention discloses a preparation method of 2,5-disubstituted furan derivatives. One carbon-carbon bond is cut off, at the same time, a novel carbon-carbon bond is established, cyclization reactions are carried out to obtain the 2,5-disubstituted fura
A highly efficient synthesis of 2,5-disubstituted furans from enyne acetates catalyzed by lewis acid and palladium
Chen, Zheng-Wang,Luo, Miao-Ting,Wen, Yue-Lu,Ye, Min,Zhou, Zhong-Gao,Liu, Liang-Xian
supporting information, p. 2341 - 2344 (2015/08/06)
A highly efficient synthesis of a wide range of 2,5-disubstituted furans from enyne acetates is described. The reactions are conducted by using Lewis acid and palladium catalyst and provide symmetrical and unsymmetrical products in good to excellent yields, with broad substrate scope, including a variety of aromatic and aliphatic substituents in the 2- and 5-position of the furan ring.
A sequential synthesis of substituted furans from aryl alkynes and ketones involving a cerium(IV) ammonium nitrate (CAN)-mediated oxidative cyclization
Undeela, Sridhar,Ramchandra, Joshi P.,Menon, Rajeev S.
, p. 5667 - 5670 (2014/12/12)
A convenient, two-step synthesis of substituted furans from readily available aryl alkynes and ketones is reported. The furan-forming oxidative cyclization is mediated by the combination of cerium(IV) ammonium nitrate and potassium bromide and can be carried out in an open flask.
