858353-45-4 Usage
Description
(9H-fluoren-9-yl)methyl 1,2-dimethylhydrazine-1-carboxylate is a chemical compound that features a fluorenyl group attached to a 1,2-dimethylhydrazine-1-carboxylate. The fluorenyl group is derived from a fluorene molecule, and the 1,2-dimethylhydrazine-1-carboxylate is a hydrazine derivative. (9H-fluoren-9-yl)methyl 1,2-dimethylhydrazine-1-carboxylate holds potential in the realm of organic chemistry and is valuable for the synthesis of a variety of organic compounds. It is crucial to handle this chemical with appropriate safety measures due to its potentially hazardous nature.
Uses
Used in Organic Chemistry:
(9H-fluoren-9-yl)methyl 1,2-dimethylhydrazine-1-carboxylate is used as a synthetic intermediate for the creation of various organic compounds. Its unique structure allows it to serve as a building block in the synthesis of complex molecules, contributing to the development of new materials and chemical products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (9H-fluoren-9-yl)methyl 1,2-dimethylhydrazine-1-carboxylate may be utilized as a precursor in the development of new drugs. Its structural properties could be harnessed to design molecules with specific therapeutic effects, potentially leading to advancements in medicinal chemistry.
Used in Material Science:
(9H-fluoren-9-yl)methyl 1,2-dimethylhydrazine-1-carboxylate may also find applications in material science, where it could be employed in the synthesis of novel materials with unique properties. These materials could have applications in various fields, such as electronics, optics, or even in the development of new types of polymers.
Check Digit Verification of cas no
The CAS Registry Mumber 858353-45-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,3,5 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 858353-45:
(8*8)+(7*5)+(6*8)+(5*3)+(4*5)+(3*3)+(2*4)+(1*5)=204
204 % 10 = 4
So 858353-45-4 is a valid CAS Registry Number.
858353-45-4Relevant articles and documents
ANTI-CD22 ANTIBODY-MAYTANSINE CONJUGATES, COMBINATIONS, AND METHODS OF USE THEREOF
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Paragraph 0597; 0614-0616, (2019/07/15)
The present disclosure provides methods for treating a cancer or resistant cancer with a combination of an anti-CD22 antibody-maytansine conjugate and one or more anti-cancer agents. The disclosure also encompasses methods for sensitizing a cancer with such combinations. Also provided are pharmaceutical compositions including such combinations.
ANTI-CD22 ANTIBODY-MAYTANSINE CONJUGATES AND METHODS OF USE THEREOF
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Paragraph 00453, (2017/08/24)
The present disclosure provides anti-CD22 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.
Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates
Albers, Aaron E.,Garofalo, Albert W.,Drake, Penelope M.,Kudirka, Romas,De Hart, Gregory W.,Barfield, Robyn M.,Baker, Jeanne,Banas, Stefanie,Rabuka, David
supporting information, p. 3 - 9 (2015/01/16)
In the context of antibody-drug conjugates (ADCs), noncleavable linkers provide a means to deliver cytotoxic small molecules to cell targets while reducing systemic toxicity caused by nontargeted release of the free drug. Additionally, noncleavable linker
