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858414-23-0

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858414-23-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 858414-23-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,4,1 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 858414-23:
(8*8)+(7*5)+(6*8)+(5*4)+(4*1)+(3*4)+(2*2)+(1*3)=190
190 % 10 = 0
So 858414-23-0 is a valid CAS Registry Number.

858414-23-0Relevant articles and documents

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

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, (2013/03/26)

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.

NEW BIARYL AMIDE DERIVATIVES

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, (2012/07/13)

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and A are as described herein, compositions including the compounds and methods of using the compounds.

Process development of a potent bradykinin 1 antagonist

Menzel, Karsten,Machrouhi, Fouzia,Bodenstein, Matthew,Alorati, Anthony,Cowden, Cameron,Gibson, Andrew W.,Bishop, Brian,Ikemoto, Norihiro,Nelson, Todd D.,Kress, Michael H.,Frantz, Doug E.

experimental part, p. 519 - 524 (2010/04/22)

As part of Merck's continued research effort on inflammation and pain, a safe synthesis of an orally bioavailable and CNS penetrant bradykinin 1 antagonist was developed and demonstrated on kilogram scale. The key step included a novel regioselective meta

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