1135531-77-9Relevant articles and documents
NEW BIARYL AMIDE DERIVATIVES
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Page/Page column 16, (2012/07/13)
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and A are as described herein, compositions including the compounds and methods of using the compounds.
Novel small molecule bradykinin B1 receptor antagonists. Part 1: Benzamides and semicarbazides
Schaudt, Marco,Locardi, Elsa,Zischinsky, Gunther,Stragies, Roland,Pfeifer, Jochen R.,Gibson, Christoph,Scharn, Dirk,Richter, Uwe,Kalkhof, Holger,Dinkel, Klaus,Schnatbaum, Karsten
scheme or table, p. 1225 - 1228 (2010/06/15)
The synthesis and SAR of two series of bradykinin B1 receptor antagonists is described. The benzamide moiety proved to be a suitable replacement for the aryl ester functionality of biaryl based antagonists. In addition, it was found that semica