85842-02-0

Basic information

• Product Name: 4,4'''-dichloro-5',5''-bis(1-pyrrolidinylmethyl)<1,1':3',1'':3'',1'''-quaterphenyl>-4'',6'-diol
• CAS NO: 85842-02-0
• Molecular Weight: 573.562
• Mol File: 85842-02-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4,4'''-dichloro-5',5''-bis(1-pyrrolidinylmethyl)<1,1':3',1'':3'',1'''-quaterphenyl>-4'',6'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'''-dichloro-5',5''-bis(1-pyrrolidinylmethyl)<1,1':3',1'':3'',1'''-quaterphenyl>-4'',6'-diol(85842-02-0)
• EPA Substance Registry System: 4,4'''-dichloro-5',5''-bis(1-pyrrolidinylmethyl)<1,1':3',1'':3'',1'''-quaterphenyl>-4'',6'-diol(85842-02-0)

Safety Data

• Hazardous Substances Data: 85842-02-0(Hazardous Substances Data)

Upstream product

• 85841-99-2 4'-chloro-5-iodo-2-methoxy<1,1'-biphenyl> 
• 85841-98-1 4'-chloro-6-methoxy<1,1'-biphenyl>-3-amine 
• 5586-88-9 1-(4-chlorophenyl)propan-2-one 
• 85842-00-8 4,4'''-dichloro-4'',6'-dimethoxy-1,1':3',1'':3'',1'''-quaterphenyl 
• 85841-97-0 4'-chloro-2-methoxy-5-nitro<1,1'-biphenyl> 
• 85841-96-9 4'-chloro-5-nitro<1,1'-biphenyl>-2-ol 
• 123-75-1 pyrrolidine 
• 50-00-0 formaldehyd 
• 85842-01-9 4,4'''-dichloro<1,1':3',1'':3'',1'''-quaterphenyl>-4'',6'-diol 

Relevant articles and documents

Camoform analogs as potential agents against mefloquine resistant malaria

Analogs of 5,5'-di-2-propenyl-3,3'-bis(1-pyrrolidinylmethyl) [1,1'-biphenyl]-4,4'-diol 2 which exhibited modest activity against chloroquine- and mefloquine-resistant lines of Plasmodium berghei were prepared. Modifications of the Mannich side chain, the propenyl group, and analogs wherein a bridging atom was inserted between the phenyl rings were prepared. None of the structural changes provided an improvement in antimalarial activity over the lead compound in the P. berghei mouse system.