858666-95-2

Upstream product

• 858666-65-6 (2S,5S,7S,1''S)-(+)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-2-formyl-1,6-dioxaspiro[4.5]decane 
• 858666-93-0 (1'E,2S,5R,7S,1''S)-(+)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-2-(3'-hydroxy-1'-propenyl)-1,6-dioxaspiro[4.5]decane 
• 858666-87-2 (2S,5S,7S,1''S)-(+)-2-(1'-benzyloxymethyl)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-1,6-dioxaspiro[4.5]decane 
• 858666-91-8 (1'E,2S,5R,7S,1''S)-(+)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-2-(2'-ethoxycarbonyl-2'-methyl-1'-propenyl)-1,6-dioxaspiro[4.5]decane 
• 786668-40-4 (2S,3S)-(-)-7-benzyloxy-1-tert-butyldiphenylsilyloxy-2-methylheptan-3-ol 
• 786668-23-3 (2S,3S)-(+)-7-benzyloxy-2-methylheptane-1,3-diol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 78999-24-3 5-benzyloxy-1-pentanal 
• 858666-83-8 4-benzenesulfonyl-1-benzyloxy-2,9-bis-(tert-butyl-dimethyl-silanyloxy)-11-(tert-butyl-diphenyl-silanyloxy)-10-methyl-undecan-5-one 
• 858666-81-6 4-benzenesulfonyl-1-benzyloxy-2,9-bis-(tert-butyl-dimethyl-silanyloxy)-11-(tert-butyl-diphenyl-silanyloxy)-10-methyl-undecan-5-ol 
• 858666-85-0 (2S,9S,10S)-(-)-1-benzyloxy-2,9-bis-(tert-butyldimethylsilyloxy)-11-(tert-butyldiphenylsilyloxy)-10-methylundecane-5-one 
• 858666-78-1 (2S,3S)-(+)-7-benzyloxy-1-tert-butyldiphenylsilyloxy-3-tert-butyldimethylsilyloxy-2-methylheptane 
• 887001-88-9 (5S,6S)-(+)-5-tert-butyldimethylsilyloxy-7-tert-butyldiphenylsilyloxy-6-methylheptan-1-ol 
• 858666-69-0 (5S,6S)-(+)-5-tert-butyldimethylsilyloxy-7-tert-butyldiphenylsilyloxy-6-methylheptan-1-al 

Downstream Products

• 858666-63-4 (1'E,2S,5R,7S,1''S)-(+)-2-(6'-benzyloxy-2'-methyl-1'-hexen-4'-yn-1'-yl)-7-{2''-(tert-butyldiphenylsilyloxy)-1''-methylethyl}-1,6-dioxaspiro[4.5]decane 

Relevant academic research and scientific papers

Synthesis of the ABC tricyclic fragment of the pectenotoxins via stereocontrolled cyclization of a γ-hydroxyepoxide appended to the AB spiroacetal unit

The stereocontrolled synthesis of the C1-C16 ABC spiroacetal-containing tricyclic fragment of pectenotoxin-7 6 has been accomplished. The key AB spiroacetal aldehyde 9 was successfully synthesized via acid catalyzed cyclization of protected ketone precurs

Synthesis of the ABC fragment of the pectenotoxins

(Chemical Equation Presented) A highly stereocontrolled synthesis of the C1-C16 ABC spiroacetal-containing fragment 5 of PTX7 (4) has been achieved. Appendage of the C ring to the AB fragment involved Wittig reaction of spiroacetal aldehyde 8 with a stabi