786668-23-3Relevant academic research and scientific papers
Synthesis of the ABC tricyclic fragment of the pectenotoxins via stereocontrolled cyclization of a γ-hydroxyepoxide appended to the AB spiroacetal unit
Halim, Rosliana,Brimble, Margaret A.,Merten, Joern
, p. 1387 - 1399 (2007/10/03)
The stereocontrolled synthesis of the C1-C16 ABC spiroacetal-containing tricyclic fragment of pectenotoxin-7 6 has been accomplished. The key AB spiroacetal aldehyde 9 was successfully synthesized via acid catalyzed cyclization of protected ketone precurs
Studies directed towards the synthesis of antascomicin A: stereoselective synthesis of the C1-C21 fragment of the molecule
Chakraborty, Tushar Kanti,Mohan, Bajjuri Krishna
, p. 4999 - 5002 (2007/10/03)
A stereoselective synthesis of the C1-C21 fragment of the non-immunosuppressive immunophilin-binding natural product, antascomicin A was achieved using, as key steps, highly stereoselective Aldol reactions to build the C1-C17 fragment and a Nozaki-Hiyama-
Synthesis of the ABC fragment of the pectenotoxins
Halim, Rosliana,Brimble, Margaret A.,Merten, Joern
, p. 2659 - 2662 (2007/10/03)
(Chemical Equation Presented) A highly stereocontrolled synthesis of the C1-C16 ABC spiroacetal-containing fragment 5 of PTX7 (4) has been achieved. Appendage of the C ring to the AB fragment involved Wittig reaction of spiroacetal aldehyde 8 with a stabi
Access to both anomers of pectenotoxin spiroketals by kinetic spiroketalization
Pihko, Petri M.,Aho, Jatta E.
, p. 3849 - 3852 (2007/10/03)
A concise synthesis of both AB ring spiroisomers of the pectenotoxins is described. The nonanomeric AB spiroketal ring system of the pectenotoxins-1, -2, -3, and -6 is formed under very mild, kinetic spiroketalization conditions, along with the anomeric i
