858806-01-6

Basic information

• Product Name: N-mesityl-N-methyl-succinamic acid
• Synonyms: N-mesityl-N-methyl-succinamic acid
• CAS NO: 858806-01-6
• Molecular Weight: 249.31
• Mol File: 858806-01-6.mol

Chemical Properties

• CAS DataBase Reference: N-mesityl-N-methyl-succinamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-mesityl-N-methyl-succinamic acid(858806-01-6)
• EPA Substance Registry System: N-mesityl-N-methyl-succinamic acid(858806-01-6)

Safety Data

• Hazardous Substances Data: 858806-01-6(Hazardous Substances Data)

Upstream product

• 108-30-5 succinic acid anhydride 
• 13021-14-2 N-methyl-2,4,6-trimethylaniline 

Downstream Products

• 500730-66-5 (+/-)-N-(3-bromo-2,4,6-trimethyl-phenyl)-N-methyl-succinamic acid 

Relevant articles and documents

HIV REVERSE TRANSCRIPTASE INHIBITORS

Compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein T is O or S; U is O, S, N(R4), or a direct bond linking V to the C(=T) moiety; V is optionally substituted C1-6 alkylene; W is C(O)N(R5) or a direct bond linking V to R3; and R1, R2, R3, R4 and R5 are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.