858972-17-5

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-(3-amino-4-fluorophenyl)acetate is utilized as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of novel drug molecules. Its unique structure, including the presence of an amino and fluorine group, allows for versatile chemical reactions that can lead to the creation of bioactive compounds with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, Ethyl 2-(3-amino-4-fluorophenyl)acetate serves as a valuable building block for the design and synthesis of new chemical entities. Its incorporation into molecular frameworks can enhance the pharmacological properties of drug candidates, such as improving their potency, selectivity, and bioavailability.
It is crucial to handle Ethyl 2-(3-amino-4-fluorophenyl)acetate with care and adhere to safety protocols due to its potential hazardous nature. Proper handling and storage are essential to ensure the safety of researchers and the integrity of experiments involving Ethyl 2-(3-amino-4-fluorophenyl)acetate.

Upstream product

• 858972-16-4 ethyl 2-(4-fluoro-3-nitrophenyl)acetate 
• 192508-36-4 2-(4-fluoro-3-nitrophenyl)acetic acid 
• 405-50-5 p-Fluorophenylacetic acid 
• 587-88-2 ethyl 2-(4-fluorophenyl)acetate 

Downstream Products

• 1442471-26-2 ethyl 2-(5-amino-2-bromo-4-fluorophenyl)acetate 
• 1012879-33-2 3-(3-amino-4-fluorophenyl)-7-chloro-1-isopropyl-1,6-naphthyridin-2(1H)-one 
• 1012878-78-2 3-(3-amino-4-fluorophenyl)-7-chloro-1-ethyl-1,6-naphthyridin-2(1H)-one 
• 858972-20-0 2-azido-4-fluorophenylacetic acid 
• 858972-25-5 8-benzyl-2-(3-azido-4-fluorophenylmethyl)-6-(4-hydroxyphenyl)-3,7-dihydroimidazo[1,2-a]pyrazin-3-one 
• 858972-22-2 (3-azido-4-fluorophenyl)methyl bromomethyl ketone 
• 858972-21-1 (3-azido-4-fluorophenyl)methyl diazomethyl ketone 
• 858972-19-7 ethyl (2-azido-4-fluorophenyl)acetate 
• 1012879-35-4 3-(3-amino-4-fluoro-phenyl)-1-isopropyl-7-methylamino-1H-[1,6]naphthyridin-2-one 

Relevant academic research and scientific papers

Method for synthesizing 2-bromo-4-fluoro-5-aminoethyl phenylacetate

The invention belongs to the technical field of preparation of intermediates of a dihydronaphthyridine compound, and particularly relates to a method for synthesizing 2-bromo-4-fluoro-5-aminoethyl phenylacetate. The method comprises the following steps: 1

Synthesis of azide-fluoro-dehydrocoelenterazine analog as a photoaffinity-labeling probe and photolysis of azide-fluoro-coelenterazine

A photosensitive azide-fluoro-dehydrocoelenterazine analog (Az-F-DCT) was synthesized, starting from 4-fluorophenylacetic acid, as a photoaffinity- labeling probe in order to analyze symplectin active site. To examine the photo-reactivity of Az-F-DCT, azi