85909-20-2Relevant academic research and scientific papers
Intramolecular Alkylation Route to the Bicyclononane Ring System. A Total Synthesis of dl-Clovene
Schultz, Arthur G.,Dittami, James P.
, p. 2318 - 2321 (1983)
A formal total synthesis of dl-clovene (9) is described.The synthesis is highlighted by the efficient intramolecular alkylation of trisubstituted cyclohexenone 11b to give 5-(2-ethylallyl)-1-methylbicyclonon-2-en-4-one (13b) in 80percent isolated yield.The preparation of 11b follows an alkylation route starting with the enol ether 3 of cyclohexane-1,3-dione.
