85972-72-1Relevant academic research and scientific papers
PROPARGYLAMINE SYNTHESIS USING A COPPER (I) CATALYSED THREE COMPONENT COUPLING REACTION
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Page/Page column 10; 12, (2012/02/01)
The present invention relates to a three component coupling reaction. In this reaction a terminal alkyne or a salt thereof, a geminal dihalide and a primary or secondary amine are reacted in the presence of a copper (I) catalyst to produce a propargylamin
Copper-catalyzed three-component coupling of terminal alkyne, dihalomethane and amine to propargylic amines
Yu, Dingyi,Zhang, Yugen
experimental part, p. 163 - 169 (2011/03/22)
The direct C-H and C-halogen activation for C-C bond formation is one of the most interesting reactions in organic chemistry. C-C bond formation using alkynes as a carbon nucleophilic source is a very useful method in synthesis. Herein, a copper(I) chlori
HYDROBORATION D'AMINES INSATUREES-II REGIO ET STEREOSELECTIVITE DE L'HYDROBORATION-ALKYLATION D'AMINES ACETYLENIQUES
Torregrosa, J. L.,Baboulene, M.,Speziale, V.,Lattes, A.
, p. 2355 - 2363 (2007/10/02)
The hydroboration reaction of acetylenic amines R1R2N-CH(R3)-CC-R4 was studied.We report the first results of a study of the reactivity of dialkylborane R2BH towards these amines which allow us to propose a new method for the synthesis of differently substituted β-ethylenic amines.The regioselectivity and the stereoselectivity of this reaction are examined and allow us to set out the possibility of a trans hydroboration.
