85974-22-7

Upstream product

• 2389-45-9 Boc-Lys(Z)-OH 
• 85974-21-6 N,N^Im-di-t-butoxycarbonyl-L-histidyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-16-9 t-butoxycarbonyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 85974-15-8 t-butoxycarbonyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 
• 68623-39-2 t-butoxycarbonyl-L-glutamine anhydride 
• 83031-02-1 t-butoxycarbonyl-L-phenylalanine 4-picolyl ester 
• 13726-85-7 Boc-Gln-OH 
• 7536-58-5 BOC-L-aspartic acid 4-benzyl ester 
• 84891-23-6 L-phenylalanine 4-picolyl ester 

Downstream Products

• 85974-24-9 t-butoxycarbonyl-O-benzyl-L-seryl-ε-benzyloxycarbonyl-L-lysyl-L-histidyl-L-glutaminyl-β-benzyl-L-aspartyl-L-phenylalanine 4-picolyl ester 

Relevant academic research and scientific papers

Amino-acids and Peptides Part 47. Synthesis of Peptides Related to Bovine Prothrombin.

It is known that Fragment 2 of bovine prothrombin inhibits the coagulation of blood plasma, and various considerations suggest that the inhibitory site might be in the 198-215 region (1) of prothrombin.Peptides related to the sequences in the 202-215 region of bovine prothrombin (2) have been synthesised by the picolyl ester method for examination as possible anticoagulation agents, including the bovine fragment 202-215 and the human fragment 204-215, variants of the sequence 210-215, and the bovine and human sequences 202-209.