85982-88-3

Upstream product

• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 4132-28-9 2,3,4,6-tetra-O-benzyl-D-mannopyranose 
• 75-77-4 chloro-trimethyl-silane 
• 3866-62-4 2,3,4,6-tetra-O-benzyl-1-O-acetyl-α-D-mannopyranose 
• 2083-91-2 N,N-Dimethyltrimethylsilylamine 
• 6386-24-9 2,3,4,6-tetra-O-benzyl-D-galactopyranose 

Downstream Products

• 131531-70-9 4-methylphenyl 2,3,4,6-tetra-O-benzyl-1-thio-α-D-mannopyranoside 
• 74666-83-4 S-ethyl 2,3,4,6-tetra-O-benzyl-1-deoxy-1-thio-α-D-mannopyranoside 
• 131531-74-3 1-S-acetyl-2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside 
• 922187-86-8 3,4,5,7-tetra-O-benzyl-1-deoxy-α-D-gluco-hept-ulopyranosyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside 
• 188819-44-5 1-Deoxy-2,3,4,6-tetra-O-benzyl-β-D-mannopyranosyl cyanide 
• 74080-40-3 (2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-2,3,4,6-tetra-O-benzyl-α-D-galactopyranoside 
• 25018-28-4 2,3,4,6-tetrabenzyl-α-D-mannopyranosyl-(1->1)-2,3,4,6-tetrabenzyl-α-D-mannopyranoside 
• 38184-10-0 phenyl 2,3,4,6-tetra-O-benzyl-1-thio-α-D-mannopyranoside 
• 131531-75-4 5-Oxo-3-((2R,3S,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-ylsulfanyl)-4,5-dihydro-[1,2,4]triazine-6-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Stereoselective trimethylsilylation of α- and β-galactopyranoses

Trimethylsilylation of the anomeric hydroxyl groups of tetra-O-benzyl and tetra-O-acetyl galactopyranoses was investigated. Stereoselective formation of β-trimethylsilyl glycoside (β-TMS glycoside) of benzyl protected compound was achieved using N-trimeth

TOLL-LIKE RECEPTOR 9 AGONISTS

The present invention provides TLR9 agonists comprising, as an active ingredient, a compound represented by formula (I): (wherein a represents 0 or 1; n represents an integer of 0 to 2; m represents an integer of 0 to 5; X1 and X2 each independently represent a hydrogen atom or hydroxy; Y represents an oxygen atom or a sulfur atom; -Q1-represents -O- or the like; -Q2- represents -O- or the like; -Z- represents -O- or the like; R1, R3 and R4 each independently represent hydroxy or the like; R2 and R5 each independently represent a hydrogen atom, hydroxy or the like; and A represents 6-aminopurin-9-yl or the like) or a pharmaceutically acceptable salt thereof, and the like.

Studies on Glycosides VII. A Highly Stereoselective Synthesis of 1-Thioglycosides

A facile method for the synthesis of 1-thioglycosides using 1-α-O-trimethylsilyl-2,3,4,6,-tetra-O-benzyl-D-gluco- or manno-pyranoside by the promotion of BF3Et2O was reported.The reaction conditions were very mild, and 1-thioglycosides were obtained in hi