860002-73-9Relevant academic research and scientific papers
Preparation of 1,4,5-trisubstituted 5-acyl-1,2,3-triazoles by selective acylation between copper(I)-carbon(sp) and copper(I)-carbon(sp2) bonds with acyl chlorides
Wang, Bo,Liu, Nan,Shao, Changwei,Zhang, Qun,Wang, Xinyan,Hu, Yuefei
, p. 2564 - 2568 (2013)
A one-pot, three-component method for preparation of 1,4,5-trisubstituted 5-acyl-1,2,3-triazoles has been developed based on a highly selective acylation of the copper(I)-carbon(sp2) bond with acyl chlorides in the presence of the copper(I)-carbon(sp) bond. The procedure is characterized by high efficiency and simple conditions. Copyright
Synthesis of 5-organostibano-1H-1,2,3-triazoles by Cu-catalyzed azide-alkyne cycloaddition and their application in the acyl-induced deantimonation for the preparation of fully substituted 5-acyl-1,2,3-triazoles
Yamada, Mizuki,Matsumura, Mio,Murata, Yuki,Kawahata, Masatoshi,Saito, Kohki,Kakusawa, Naoki,Yamaguchi, Kentaro,Yasuike, Shuji
, p. 2614 - 2622 (2017/04/07)
The Cu-catalyzed azide-alkyne cycloaddition by the reaction of various ethynylstibanes with benzylazide in the presence of CuBr (5?mol%) under aerobic conditions led to the formation of trisubstituted 5-organostibano-1H-1,2,3-triazoles. Further, the acyl-induced deantimonation of 5-stibanotriazoles with acyl chlorides in the presence of N,N-dimethyl-4-aminopyridine and triethylamine afforded the corresponding trisubstituted 5-acyltriazoles in moderate-to-good yields.
Metal- and base-free three-component reaction of ynones, sodium azide, and Alkyl Halides: Highly regioselective synthesis of 2,4,5-trisubstituted 1,2,3- NH -triazoles
Li, Jihui,Zhang, Yuanqing,Wang, Dong,Wang, Wen,Gao, Tingting,Wang, Lu,Li, Jiting,Huang, Guosheng,Chen, Baohua
supporting information; experimental part, p. 1617 - 1622 (2010/09/05)
A base- and metal-free three-component reaction of ynones, sodium azide, and alkyl halides is developed for the regioselective synthesis of 2,4,5-trisubstituted-1,2,3-triazoles. The method is general, convenient, environmentally benign, atom-economical, and high-yielding.
Conformational control in the regioselective synthesis of N-2-substituted-1,2,3-triazoles
Chen, Yunfeng,Liu, Yuxiu,Petersen, Jeffrey L.,Shi, Xiaodong
supporting information; experimental part, p. 3254 - 3256 (2009/02/04)
An effective strategy for the synthesis of N-2-substituted-1,2,3-triazoles with excellent yields and regioselectivity has been developed. The Royal Society of Chemistry.
Regiospecific synthesis of 1,4,5-trisubstituted-1,2,3-triazole via one-pot reaction promoted by copper(I) salt
Wu, Yong-Ming,Deng, Juan,Li, Ya,Chen, Qing-Yun
, p. 1314 - 1318 (2007/10/03)
A method for the regiospecific synthesis of 1,4,5-trisubstituted-1,2,3- triazole catalyzed by copper(I) iodide was developed. This is the first example of a regiospecific synthesis of 5-iodo-1,4-disubstituted-1,2,3-triazole, which can be further elaborated to a range of 1,4,5-trisubstituted-1,2,3-triazole derivatives. Georg Thieme Verlag Stuttgart.
