860002-80-8Relevant academic research and scientific papers
Nafion-H: An efficient and recyclable heterogeneous catalyst for the one-pot synthesis of 2,3-disubstituted 4-(3H)-quinazolinones under solvent-free microwave irradiation conditions
Lingaiah, B. Venkat,Ezikiel,Yakaiah,Reddy, G. Venkat,Shanthan Rao
, p. 2507 - 2509 (2008/02/11)
A one-pot synthesis of 2,3-disubstituted 4-(3H)-quinazolinones has been carried out efficiently by the three-component coupling of isatoic anhydride/anthranilic acid, orthoesters, and amines in the presence of Nafion-H (a perfluorinated resin-supported su
Synthesis and structure-activity relationship of 3-phenyl-3H-quinazolin-4- one derivatives as CXCR3 chemokine receptor antagonists
Storelli, Stefania,Verdijk, Pauline,Verzijl, Dennis,Timmerman, Henk,Van De Stolpe, Andrea C.,Tensen, Cornelis P.,Smit, Martine J.,De Esch, Iwan J. P.,Leurs, Rob
, p. 2910 - 2913 (2007/10/03)
A series of 3-phenyl-3H-quinazolin-4-ones have been synthesized and tested for affinity and activity at the chemokine CXCR3 receptor. The most potent compound (1d) has been evaluated using radioligand binding and calcium mobilization assays and is considered a useful tool for further characterization of the CXCR3 receptor.
