860036-40-4

Upstream product

• 860036-39-1 (R,R)-O,O'-bistrimethylsilylcyclohexyl-1,2-dihydroxylamine 
• 79271-56-0 triethylsilyl trifluoromethyl sulfonate 
• 525585-56-2 (1R,2R,N₁E,N₂E)-N₁,N₂-bis(4-methoxybenzylidene)cyclohexane-1,2-diamine 
• 32044-22-7 (1R,2R)-1,2-diaminocyclohexane tartrate 
• 860036-37-9 C₂₂H₂₆N₂O₄ 
• 994-30-9 triethylsilyl chloride 

Downstream Products

• 1217463-44-9 (R,R)-N-(2-{[2,2-bis(3,5-dimethylphenyl)acetyl]hydroxyamino}cyclohexyl)-2,2-bis(3,5-dimethylphenyl)-N-hydroxyacetamide 
• 860036-16-4 (R,R)-N-[2-(diphenylacetylhydroxyamino)cyclohexyl]-N-hydroxy-2,2-diphenylacetamide 
• 860036-29-9 (R,R)-N-hydroxy-N-{2-[hydroxy-(3,3,3-triphenylpropionyl)amino]cyclohexyl}-3,3,3-triphenylpropionamide 

Relevant academic research and scientific papers

Catalytic asymmetric epoxidation

The present invention relates to the synthesis of chiral epoxides via a catalytic asymmetric oxidation of olefins. Additionally, the methodology provides a method of asymmetrically oxidizing sulfides and phosphines. This asymmetric oxidation employs a catalyst system composed of a metal and a chiral bishydroxamic acid ligand, which, in the presence of a stoichiometric oxidation reagent, serves to asymmetrically oxidize a variety of substrates.

Enantioselective epoxidation of allylic alcohols by a chiral complex of vanadium: An effective controller system and a rational mechanistic model

(Chemical Equation Presented) Bishydroxamic acid derivatives are used as ligands for a vanadium catalyst in the preparation of epoxy alcohols (see scheme). The methodology uses aqueous tert-butyl hydroperoxide (TBHP) as an achiral oxidant, low catalyst loading, low reaction temperatures (0°C to room temperature), and simple workup procedures. The reaction is applied to the kinetic resolution of a secondary allylic alcohol and the preparation of small epoxy alcohols. R1, R2, R3: alkyl, aryl, H.