86014-52-0Relevant academic research and scientific papers
AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS
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Page/Page column 39-40, (2009/04/25)
New azabiphenylaminobenzoic acid derivatives having the chemcial structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of the dehydroorotate dihydrogenase (DHODH)
Ring Transformations in Reactions of Heterocyclic Compounds with Nucleophiles. 1,3- and 1,4-Cycloadducts as Intermediates in the Pyrimidine to Pyridine Ring Transformation of 5-Nitropyrimidines by α-Phenylacetamidines
Charushin, Valery N.,Plas, Henk C. van der
, p. 2667 - 2671 (2007/10/02)
5-Nitropyrimidine reacts with α-phenylacetamidines at -40 deg C to form ? adducts at the C-2 position of the ring but gives 2-aminopyridine derivatives at temperatures above 0 deg C.Experiments with 15N-labeled α-phenylacetamidine have shown th
