86026-81-5

Basic information

• Product Name: 2,5-DIIODO-1-METHYLIMIDAZOLE
• Synonyms: 2,5-Diiodo-1-methyl-1H-imidazole97%;2,5-DIIODO-1-METHYL-1H-IMIDAZOLE;2,5-DIIODO-1-METHYLIMIDAZOLE;2,5-Diiodo-1-methyl-1H-imidazole 97%;1H-Imidazole,2,5-diiodo-1-methyl-
• CAS NO: 86026-81-5
• Molecular Formula: C4H4I2N2
• Molecular Weight: 333.9
• Product Categories: blocks;Imidazoles;Iodides
• Mol File: 86026-81-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 138-143
• Boiling Point: 351.6 °C at 760 mmHg
• Flash Point: 166.4 °C
• Appearance: /
• Density: 2.83 g/cm³
• Vapor Pressure: 4.07E-05mmHg at 25°C
• Refractive Index: 1.803
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2,5-DIIODO-1-METHYLIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIIODO-1-METHYLIMIDAZOLE(86026-81-5)
• EPA Substance Registry System: 2,5-DIIODO-1-METHYLIMIDAZOLE(86026-81-5)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 86026-81-5(Hazardous Substances Data)

Usage

Uses

It is employed as intermediate for pharmaceutical.

InChI:InChI=1/C4H4I2N2/c1-8-3(5)2-7-4(8)6/h2H,1H3

Upstream product

• 616-47-7 1-methyl-1H-imidazole 

Downstream Products

• 71759-88-1 5-iodo-1N-methyl imidazole 

Relevant articles and documents

T -BuONa-mediated direct C-H halogenation of electron-deficient (hetero)arenes

An efficient halogenation of electron-deficient (hetero)arenes is described. The reaction utilizes common t-BuONa as a catalyst (for iodination) or a promoter (for bromination and chlorination), and perfluorobutyl iodide, CBr4 or CCl4 as the readily-available halogenating agents, respectively. The protocol features broad scope, high efficiency, mild conditions and gram scalability. An ionic pathway involving halogen bond formation and halophilic attack is proposed. The utility of the resulting iodinated heteroarenes is demonstrated in visible light-mediated Caryl-Caryl cross-coupling reaction.

A new, mild one-pot synthesis of iodinated heterocycles as suitable precursors for N-heterocyclic carbene complexes

The use of I2/AgOAc in dichloromethane constitutes a cheap, mild, and efficient method for the selective iodination of a variety of heterocycles. In a number of cases, this method provides superior yields to other literature methods and affords iodo-functionalized heterocycles that are suitable precursors for carbene complexes.

SYNTHESIS OF HALOGEN DERIVATIVES OF N-METHYLIMIDAZOLE

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