86030-46-8

Upstream product

• 288-88-0 1,2,4-Triazole 
• 13368-42-8 4-(trimethylsilyl)morpholine 
• 3279-26-3 methyl dichlorophosphite 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 86030-42-4 morpholinomethylphosphonamidic chloride 

Downstream Products

• 78635-91-3 Dimethyl-phosphoramidous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester methyl ester 
• 2476-56-4 5'-d(TpTp)-3' 
• 136340-65-3 C₆₃H₆₀N₇O₁₄PS 
• 86733-54-2 Phosphorous acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester dimethyl ester 

Relevant academic research and scientific papers

AN INVESTIGATION OF SEVERAL DEOXYNUCLEOSIDE PHOSPHORAMIDITES USEFUL FOR SYNTHESIZING DEOXYOLIGONUCLEOTIDES

Various deoxynucleoside N,N-dialkylaminomethoxyphosphines were examined for stability and reactivity in deoxyoligonucleotide synthesis.Of those examined, the N-morpholino and N,N-diisopropylamino derivatives most completely satisfied all criteria.

A NEW AND GENERAL PROCEDURE FOR THE PREPARATION OF DEOXYNUCLEOSIDE PHOSPHORAMIDITES

Nucleoside phosphoramidites can be obtained in a one pot reaction by reacting successively an alkyloxy (or aryloxy)bis-triazolylphosphine with 3'-OH free deoxynucleoside and a trimethylsilylated secondary amine.