860606-17-3Relevant academic research and scientific papers
Synthesis and cerebral uptake of 1-(1-[11C]methyl-1H-pyrrol-2- yl)-2-phenyl-2-(1-pyrrolidinyl)ethanone, a novel tracer for positron emission tomography studies of monoamine oxidase type A
Jensen, Svend Borup,Di Santo, Roberto,Olsen, Aage Kristian,Pedersen, Kasper,Costi, Roberta,Cirilli, Roberto,Cumming, Paul
, p. 1617 - 1622 (2008/12/20)
(R)-(-)- and (S)-(+)-1-(1-[11C]methyl-1H-pyrrol-2-yl)-2-phenyl- 2-(1-pyrrolidinyl)ethanone 4 and 5 were synthesized, and their properties as tracers for positron emission tomography (PET) studies of monoamine oxidase type A (MAO-A) in the brain
Design, synthesis, and biological activities of pyrrolylethanoneamine derivatives, a novel class of monoamine oxidases inhibitors
Di Santo, Roberto,Costi, Roberta,Roux, Alessandra,Artico, Marino,Befani, Olivia,Meninno, Tiziana,Agostinelli, Enzo,Palmegiani, Paola,Turini, Paola,Cirilli, Roberto,Ferretti, Rosella,Gallinella, Bruno,La Torre, Francesco
, p. 4220 - 4223 (2007/10/03)
Pyrrolylethanoneamines 1-12, 18-23 and related amino alcohols 13-15, 24-27 were synthesized and tested against monoamine oxidases A and B (MAO-A and MAO-B) enzymes. In general, aminoketones 1-12, 18-23 were found to be potent and selective MAO-A inhibitor
