860640-72-8

Upstream product

• 860640-70-6 1,3,2',6'-tetraazido-3',4'-dideoxy-3'-enoneamine 
• 98-88-4 benzoyl chloride 
• 688744-65-2 1,3,2’,6’-tetrazido-5,6-O-cyclohexylidene neamine 
• 671809-10-2 1,3,2′,6′-tetraazidoneamine 
• 1053694-75-9 C₂₀H₂₄F₆N₁₂O₁₀S₂ 
• 860640-71-7 C₁₈H₂₄N₁₂O₄ 

Downstream Products

• 912671-26-2 (2S,3R,4S,5S,6R)-5-Amino-2-[(1R,2R,3S,5R,6S)-3,5-diamino-2-((2R,3R,6S)-3-amino-6-aminomethyl-3,6-dihydro-2H-pyran-2-yloxy)-6-hydroxy-cyclohexyloxy]-6-methyl-tetrahydro-pyran-3,4-diol 
• 860640-74-0 (2S,3R,4S,5S,6R)-5-Azido-2-[(1R,2R,3S,5R,6S)-3,5-diazido-2-((2R,3R,6S)-3-azido-6-azidomethyl-3,6-dihydro-2H-pyran-2-yloxy)-6-hydroxy-cyclohexyloxy]-6-methyl-tetrahydro-pyran-3,4-diol 

Relevant academic research and scientific papers

Novel anti bacterial compounds

The invention relates to novel paranmycin compounds that have activity against gram positive and gram negative bacteria, preferably bacteria that are resistant to other antibiotics. Paranmycins are of the general formula

Novel method for the synthesis of 3′,4′-dideoxygenated pyranmycin and kanamycin compounds, and studies of their antibacterial activity against aminoglycoside-resistant bacteria

A novel protocol for converting a trans-diol to an alkene under mild conditions was developed. This method led to the synthesis of a 3′,4′-dideoxykanamycin (dibekacin) analog and a 3′,4′- dideoxypyranmycin that were found to be active against aminoglycosi