86119-02-0Relevant academic research and scientific papers
Diastereoselective construction of 7-methylenebicyclo[3.2.1]oct-3-en-2-one derivatives by palladium-catalyzed cyclization of propargylic acetates with 2-oxocyclohex-3-enecarboxylates
Yoshida, Masahiro,Sugimura, Chiyuki,Shishido, Kozo
supporting information; experimental part, p. 3482 - 3485 (2011/09/13)
The reaction of propargylic acetates with 2-oxocyclohex-3-enecarboxylates in the presence of a palladium catalyst is described. Substituted 7-methylenebicyclo[3.2.1]oct-3-en-2-ones were synthesized in a highly diastereoselective manner.
Rapid Access to a Highly Functionalized Tricyclic Bruceantin Intermediate
Pariza, R. J.,Fuchs, P. L.
, p. 2306 - 2308 (2007/10/02)
Having found several B -> (AB or BC) -> ABC ring formation strategies unsuited for the synthesis of bruceantin and other quassinoids, we have successfully produced a highly functionalized intermediate, of desired stereochemistry, from a C -> -> ABC a
