861256-13-5Relevant academic research and scientific papers
Organocatalytic asymmetric direct alkylation of α-diazoester via C-H bond cleavage
Uraguchi, Daisuke,Sorimachi, Keiichi,Terada, Masahiro
, p. 9360 - 9361 (2005)
A new variant of phosphoric acid-catalyzed C-C bond forming reaction, direct alkylation of α-diazoester, via C-H bond cleavage is presented. The resulting products, β-amino-α-diazoesters, are highly functionalized and useful synthetic precursors for vario
Process for production of amines
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Page/Page column 49-58, (2008/06/13)
A process for producing an amine which is characterized by reacting an imine with a nucleophilic compound (except a trialkylsilyl vinyl ether) in the presence of a phosphoric acid derivative represented by the formula (1): wherein A1 represents a spacer; X1 and X2 represent each independently a divalent nonmetal atom or a divalent nonmetal atomic group; and Y1 is oxygen or sulfur. The invention provides a process by which amines (particularly optically active amines) useful as intermediates of medicines, agricultural chemicals, or the like can be produced without special post-treatment in high yield at high optical purity; and phosphoric acid derivatives (particularly optically active phosphoric acid derivatives) useful in the production of the amines.
