861335-99-1

Upstream product

• 3484-35-3 5-methylindolin-2-one 
• 100-52-7 benzaldehyde 

Downstream Products

• 1003321-25-2 (2R,3R)-ethyl 2-(3-benzyl-5-methyl-2-oxoindolin-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate 
• 1003321-14-9 (2S,3S)-ethyl 2-(3-benzyl-5-methyl-2-oxoindolin-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate 
• 1351708-00-3 C₂₆H₃₃N₃O₅ 
• 1398681-73-6 3-benzyl-3-bromo-5-methylindolin-2-one 
• 1398681-43-0 benzaldehyde O-3-benzyl-5-methyl-2-oxoindolin-3-yl oxime 
• 1043872-75-8 tert-butyl 3-benzyl-5-methyl-2-oxoindoline-1-carboxylate 

Relevant academic research and scientific papers

Organocatalytic enantioselective stereoablative hydroxylation of 3-halooxindoles: An effective method for the construction of enantioenriched 3-substituted 3-hydroxy-2-oxindoles

3-Substituted oxindoles as electrophilic partners: An unprecedented method for the construction of hydroxylated 3-substituted oxindoles in high yields and excellent enantioselectivities through stereoablative hydroxylation of 3-halooxindoles with an organocatalyst has been developed. This process not only differs from the common convention of using 3-substituted oxindoles as nucleophiles, but also provides a viable entry to optically active 3-substituted 3-hydroxy-2-oxindoles (see scheme).