861445-91-2 Usage
Uses
Used in Organic Synthesis:
Tris(trimethylsilyl)silyloxyethylene, Vinyloxytris(trimethylsilyl)silane is used as a silyl protecting group for diastereoselective [2+2] cyclizations, cross-Aldol cascade reactions, and diastereoselective sequential reactions for generating polyols. It is particularly useful for accessing distinct diastereomers and 4-component reactions.
Used in Supersilyl-Directed Aldol Reactions:
In supersilyl-directed aldol reactions, Tris(trimethylsilyl)silyloxyethylene, Vinyloxytris(trimethylsilyl)silane is used to achieve high levels of diastereoselectivity. The strong electron-donating effect of the supersilyl group operates only in the α-position, which allows for the selective formation of desired products in these reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 861445-91-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,4,4 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 861445-91:
(8*8)+(7*6)+(6*1)+(5*4)+(4*4)+(3*5)+(2*9)+(1*1)=182
182 % 10 = 2
So 861445-91-2 is a valid CAS Registry Number.
861445-91-2Relevant academic research and scientific papers
Tris(trimethylsilyl)silyl-governed aldehyde cross-aldol cascade reaction
Boxer, Matthew B.,Yamamoto, Hisashi
, p. 48 - 49 (2007/10/03)
The use of the tris(trimethylsilyl)silyl (TTMSS) group in aldehyde-derived silyl enol ethers affords aldehyde cross-aldol products with high yields and allows for unprecedented reactivity. The reaction is catalyzed by 0.05 mol % of HNTf2, and c
