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3-(4-Chloro-phenyl)-piperazin-2-one is a chemical compound belonging to the piperazine class, characterized by the presence of a core piperazine functional group and a chlorine atom substitution on the phenyl ring. Its specific physical and chemical properties, such as boiling point, melting point, and solubility, are determined by its molecular structure. Further research, including biological assays or screening, would be necessary to explore its potential uses or biological activities. Appropriate safety measures should be taken when handling 3-(4-CHLORO-PHENYL)-PIPERAZIN-2-ONE.

86147-28-6

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86147-28-6 Usage

Uses

As the provided materials do not specify the exact applications of 3-(4-Chloro-phenyl)-piperazin-2-one, it is not possible to list its uses based on the given information. Further research and investigation would be required to determine its potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 86147-28-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,1,4 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 86147-28:
(7*8)+(6*6)+(5*1)+(4*4)+(3*7)+(2*2)+(1*8)=146
146 % 10 = 6
So 86147-28-6 is a valid CAS Registry Number.

86147-28-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(4-Chlorophenyl)piperazin-2-one

1.2 Other means of identification

Product number -
Other names 3-(4-chlorophenyl)piperazin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:86147-28-6 SDS

86147-28-6Relevant academic research and scientific papers

Discovery of novel 2-(3-phenylpiperazin-1-yl)-pyrimidin-4-ones as glycogen synthase kinase-3β inhibitors

Usui, Yoshihiro,Uehara, Fumiaki,Hiki, Shinsuke,Watanabe, Kazutoshi,Tanaka, Hiroshi,Shouda, Aya,Yokoshima, Satoshi,Aritomo, Keiichi,Adachi, Takashi,Fukunaga, Kenji,Sunada, Shinji,Nabeno, Mika,Saito, Ken-Ichi,Eguchi, Jun-ichi,Yamagami, Keiji,Asano, Shouichi,Tanaka, Shinji,Yuki, Satoshi,Yoshii, Narihiko,Fujimura, Masatake,Horikawa, Takashi

, p. 3726 - 3732 (2017/07/27)

We herein describe the results of further evolution of glycogen synthase kinase (GSK)-3β inhibitors from our promising compounds containing a 2-phenylmorpholine moiety. Transformation of the morpholine moiety into a piperazine moiety resulted in potent GSK-3β inhibitors. SAR studies focused on the phenyl moiety revealed that a 4-fluoro-2-methoxy group afforded potent inhibitory activity toward GSK-3β. Based on docking studies, new hydrogen bonding between the nitrogen atom of the piperazine moiety and the oxygen atom of the main chain of Gln185 has been indicated, which may contribute to increased activity compared with that of the corresponding phenylmorpholine analogues. Effect of the stereochemistry of the phenylpiperazine moiety is also discussed.

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