861573-48-0

Basic information

• Product Name: 1-(azidomethyl)-4-isopropylbenzene
• Synonyms: 1-(azidomethyl)-4-isopropylbenzene
• CAS NO: 861573-48-0
• Molecular Weight: 175.233
• Mol File: 861573-48-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(azidomethyl)-4-isopropylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(azidomethyl)-4-isopropylbenzene(861573-48-0)
• EPA Substance Registry System: 1-(azidomethyl)-4-isopropylbenzene(861573-48-0)

Safety Data

• Hazardous Substances Data: 861573-48-0(Hazardous Substances Data)

Upstream product

• 2051-18-5 4-isopropylbenzyl chloride 
• 99-87-6 4-methylisopropylbenzene 
• 73789-86-3 4-i-propylbenzyl bromide 
• 7664-93-9 sulfuric acid 

Downstream Products

• 1187734-43-5 C₂₅H₂₉N₅O₇ 
• 59528-28-8 4-isopropylbenzylamine hydrochloride 
• 13816-33-6 p-Cyanocumen 

Relevant articles and documents

Benzylic C-H Azidation Using the Zhdankin Reagent and a Copper Photoredox Catalyst

An azidation method for C-N bond formation at benzylic C-H positions is described using copper-catalyzed visible light photochemistry and the Zhdankin azidoiodinane reagent. The method is applicable to a wide range of substrates bearing different functional groups and having a primary, secondary, or tertiary benzylic position, and is thought to proceed through a radical chain reaction.

Synthesis of novel pyrazoline-based bis(1,2,3-triazole) scaffolds via click chemistry

A series of novel bis(1,2,3-triazoles) derivatives 7a-m were synthesized by the 1,3-dipolar cycloaddition (click-reaction) of 1-methyl-3,5-bis(2-(prop-2-yn-1-yloxy)phenyl)-4,5-dihydro-1H-pyrazole (5) with various aralkyl azides 6a-m in the presence of sod

Copper promoted synthesis of substituted quinolines from benzylic azides and alkynes

A novel copper promoted synthesis of substituted quinolines from various benzylic azides and internal alkynes has been demonstrated. The reaction features a broad substrate scope, high product yields and excellent regioselectivity. In contrast to the known two-step process of acid promoted [4 + 2] cycloaddition reaction and oxidation, the present methodology allows the synthesis of quinolines in a single step under neutral reaction conditions and can be applied to the synthesis of biologically active 6-chloro-2,3-dimethyl-4-phenylquinoline (antiparasitic agent) and 3,4-diphenylquinolin-2(1H)-one (p38αMAP kinase inhibitor). A plausible reaction mechanism involves rearrangement of benzylic azide to N-arylimine (Schmidt reaction) followed by intermolecular [4 + 2] cycloaddition with internal alkynes.